A MICROBIOLOGICAL ASSAY FOR DETERMINING SARAFLOXACIN AND OXOLINIC ACID CONCENTRATIONS IN ATLANTIC SALMON PLASMA

Authors
GILES JS HARIHARAN H HEANEY SB
Citation
Js. Giles et al., A MICROBIOLOGICAL ASSAY FOR DETERMINING SARAFLOXACIN AND OXOLINIC ACID CONCENTRATIONS IN ATLANTIC SALMON PLASMA, The New microbiologica, 17(2), 1994, pp. 155-158
Citations number
NO
Categorie Soggetti
Microbiology
Journal title
The New microbiologica
ISSN journal
11217138 → ACNP
Volume
17
Issue
2
Year of publication
1994
Pages
155 - 158
Database
ISI
SICI code
1121-7138(1994)17:2<155:AMAFDS>2.0.ZU;2-3
Abstract
A microbiological assay was developed to quantify the concentrations o f the quinolone antibiotics sarafloxacin and oxolinic acid in Atlantic salmon (Salmo salar) plasma. The assay was a modification of the Asso ciation of Official Analytical Chemists (AOAC) method for antibiotic c oncentrations in feeds using disk diffusion and a lawn of Vibrio angui llarum ATCC 19264 as the test organism. With these modifications, sens itivities of 0.04 mu g/mL for sarafloxacin and 0.125 mu g/mL for oxoli nic acid were obtained.