Ly. Zhuleva et al., DETECTION OF MICRONUCLEI IN DESQUAMOUS CE LLS OF ORAL CAVITY MUCOSA IN SOUTH VIETNAMESE WOMEN, Genetika, 32(12), 1996, pp. 1700-1704
The possibility of applying the micronucleus test to estimate changes
in chromatin structures of somatic cells of South Vietnam inhabitants
exposed to with phytotoxic substances (Agent Orange) in the 1960s was
investigated. Remote medical and biological consequences of the action
of dioxin-containing phenoxyherbicides on man were studied. In inhabi
tants of Bin Mi Village (Shongbe Province), which had been intensely b
ombed with Agent Orange, the epithelium of the oral cavity showed a co
nsiderable increase in the occurrence of cells with damaged chromatin
structures (P < 0.01).