MISSHAPEN ENCODES A PROTEIN-KINASE INVOLVED IN CELL-SHAPE CONTROL IN DROSOPHILA

Authors
TREISMAN JE ITO N RUBIN GM
Citation
Je. Treisman et al., MISSHAPEN ENCODES A PROTEIN-KINASE INVOLVED IN CELL-SHAPE CONTROL IN DROSOPHILA, Gene, 186(1), 1997, pp. 119-125
Citations number
43
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
186
Issue
1
Year of publication
1997
Pages
119 - 125
Database
ISI
SICI code
0378-1119(1997)186:1<119:MEAPII>2.0.ZU;2-O
Abstract
We have identified a novel protein kinase encoded by the misshapen gen e, which is required for the normal shape and orientation of Drosophil a photoreceptor cells. misshapen is also expressed in the embryonic me soderm, pole plasm and other sites of cell shape change or movement. W e propose that msn may act in a signal transduction pathway leading to cytoskeletal re-arrangements.