IMMUNITY DISORDERS IN PATIENTS WITH LICHE N RUBER AND METHODS OF CORRECTION THEREOF

Immunologic analysis of the blood of patients with lichen ruber (n=200 ) involved not only quantitative, but functional analysis of the lymph ocytes as well - the chemiluminescence response to PHA mitogen and the ir electrophoretic mobility studies by cellular preparative electropho resis with the Elphor VaP-5 apparatus (Bender Hobein, Germany). Such a selection of the immunologic tests is pathogenetically valid. Signifi cant disorders in the immune response were found, evidencing a high fu nctional activity and poor differentiation of T lymphocytes. Vilozen, an immunomodulator made in this country, is suggested for the treatmen t of patients with lichen planus, that is conducive to correction of t he immunity shifts. Indications for the administration of the drug hav e been defined.