Systemic lupus erythematosus (SLE) has been described by many authors
as a multisystem disorder involving variable and protean clinical mani
festations and with an unpredictable course. We report the case of a 6
8-year-old woman suffering from SLE in whom tremor appeared ten years
before a clinical picture suggestive of SLE and which remained the onl
y clinical neurological sign even during overt disease. Tremor and oth
er SLE manifestations disappeared with corticosteroid therapy.