ASCORBIC-ACID, GLUCOSE, TOTAL PROTEIN, AL AT AND ASAT LEVELS IN BLOOD-PLASMA OF CLINICALLY INTACT SHEEP AND OF PARASITIZED ANIMALS (FASCIOLIASIS, ABOMASO-INTESTINAL PARASITES, LUNGWORMS) PRIOR TO AND FOLLOWINGINTRAVENOUS-INJECTION OF ASCORBIC-ACID SOLUTION

In 5 healty sheep (body mass 60,6 +/- 3,6 kg) on 3 days in the morning the content of ascorbic acid, of glucose and of total protein as well as the activity of the ALAT and the ASAT in the plasma were analysed. On the 3rd day a dose of 10 and after some days of 20 mg ascorbic aci d per kg body mass were i. v. injected. After 5 minutes there was a co ntent of ascorbic acid of 109 +/- 18 after the injection of the lower dose respectively of 156 +/- 17 mug/ml after that of the higher dose. In sheeps (n = 5 in each group) with fasciolosis, with abomasum-intest ine-parasites and with lung-worms the content of ascorbic acid in the plasma was lower than in healthy sheeps. After the injection of the me ntioned amount of ascorbic acid the content in the plasma after 5 minu tes was lower. In sheeps with fasciolosis the activity of the ALAT and the ASAT in the plasma was higher than in healthy sheeps. Sheeps infe cted with abomasum-intestine-parasites had a smaller body weight and a lower content of glucose in the plasma.