TRANSITION-METAL-CATALYZED ANNULATION REACTIONS .7. PALLADIUM-CATALYZED C-H ACTIVATION AT METHOXY GROUPS - REGIOCHEMISTRY OF THE DOMINO COUPLING PROCESSES

Authors
DYKER G
Citation
G. Dyker, TRANSITION-METAL-CATALYZED ANNULATION REACTIONS .7. PALLADIUM-CATALYZED C-H ACTIVATION AT METHOXY GROUPS - REGIOCHEMISTRY OF THE DOMINO COUPLING PROCESSES, Chemische Berichte, 127(4), 1994, pp. 739-742
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Chemische Berichte → ACNP
ISSN journal
00092940
Volume
127
Issue
4
Year of publication
1994
Pages
739 - 742
Database
ISI
SICI code
0009-2940(1994)127:4<739:TAR.P>2.0.ZU;2-M
Abstract
By palladium catalysis substituted ortho-iodoanisoles (5, 8, 10, 13) a re transformed either to annulated pyran (6) or furan derivatives (7, 9, 11, 14, 15), depending on the reactivity of additional substituents . The regiochemistry of the domino coupling processes is analyzed and a mechanistic rationale developed. Key step is the C-H activation at m ethoxy groups.