CHARACTERIZATION OF MITOCHONDRIAL-DNA PRIMASE FROM SACCHAROMYCES-CEREVISIAE

Authors
MURTHY V PASUPATHY K
Citation
V. Murthy et K. Pasupathy, CHARACTERIZATION OF MITOCHONDRIAL-DNA PRIMASE FROM SACCHAROMYCES-CEREVISIAE, Journal of Biosciences, 19(1), 1994, pp. 1-8
Citations number
20
Categorie Soggetti
Biology
Journal title
Journal of Biosciences → ACNP
ISSN journal
02505991
Volume
19
Issue
1
Year of publication
1994
Pages
1 - 8
Database
ISI
SICI code
0250-5991(1994)19:1<1:COMPFS>2.0.ZU;2-T
Abstract
DNA primase from yeast mitochondria was shown to have a molecular weig ht of 67 kDa by SDS-PAGE and an S value of 5.5. It was shown to have p reference for SS mitochondrial DNA especially fragments containing ori gins of replication, as a template to initiate DNA replication. Furthe r examination of the enzyme showed its possible association with a rib onucleotide moiety essential for enzyme activity.