TREATMENT OF METASTATIC PULMONARY TUMORS BY BRONCHIAL ARTERIAL INFUSION CHEMOTHERAPY IN 2 PATIENTS WITH LOCALLY WELL-CONTROLLED UTERINE-CANCER

Pulmonary metastatic tumors in two patients with locally well controll ed uterine cancer were treated with bronchial arterial infusion chemot herapy. The first patient underwent a radical hysterectomy and pelvic lymphadenectomy for stage IIb cervical cancer. Fifteen months after th e operation, pulmonary metastasis was identified. Clinical evidence of tumor was negative after bronchial arterial infusion chemotherapy, sy stemic chemotherapy and radiotherapy. The patient continues to be heal thy without recurrent signs six years after bronchial arterial infusio n chemotherapy. The second patient underwent a radical hysterectomy an d pelvic lymphadenectomy for stage II endometrial cancer. Fifteen mont hs after the operation, pulmonary metastasis was identified. After bro nchial arterial infusion chemotherapy and systemic chemotherapy, regre ssion of the tumors was observed. This patient has also survived for t wo years since the lung metastases. These results indicate that bronch ial arterial infusion chemotherapy is a potent treatment for pulmonary metastases of uterine cancer.