Urinary total sialic acid/creatinine (TSA/Cr) ratio was determined in
73 patients with superficial bladder tumors and 34 healthy volunteers.
The mean TSA/Cr value in the tumor group was higher than the control
group (P < 0.001) and this difference was significant. Comparing the u
rinary TSA/Cr ratio of T-1, T-a, grade I-II, grade III, single, multip
le, primary and recurrent tumors, with the control group revealed sign
ificant results (P < 0.001). Therefore the urinary TSA/Cr ratio determ
ination in the follow-up of these patients may be used as a non-invasi
ve procedure.