MOENOMYCIN-A - REACTIONS AT THE LIPID PART - NEW STRUCTURE-ACTIVITY RELATIONS

Authors
MARZIAN S HAPPEL M WAGNER U MULLER D WELZEL P FEHLHABER HW STARK A SCHUTZ HJ MARKUS A LIMBERT M VANHEIJENOORT Y VANHEIJENOORT J
Citation
S. Marzian et al., MOENOMYCIN-A - REACTIONS AT THE LIPID PART - NEW STRUCTURE-ACTIVITY RELATIONS, Tetrahedron, 50(18), 1994, pp. 5299-5308
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
18
Year of publication
1994
Pages
5299 - 5308
Database
ISI
SICI code
0040-4020(1994)50:18<5299:M-RATL>2.0.ZU;2-R
Abstract
Methods for the removal and the oxidation of the lipid moiety of the a ntibiotic moenomycin A have been studied. Combined with biochemical st udies,the results demonstrate that antibiotic activity is closely rela ted with the integrity of the lipid unit.