CHEMICAL MODIFICATION OF GLYCOSAMINOGLYCANS - O-CARBOXYMETHYLATION OFHEPARAN-SULFATE

Authors
KOVENSKY J CIRELLI AF
Citation
J. Kovensky et Af. Cirelli, CHEMICAL MODIFICATION OF GLYCOSAMINOGLYCANS - O-CARBOXYMETHYLATION OFHEPARAN-SULFATE, Anales de la Asociacion Quimica Argentina, 82(1), 1994, pp. 25-30
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Anales de la Asociacion Quimica Argentina → ACNP
ISSN journal
03650375
Volume
82
Issue
1
Year of publication
1994
Pages
25 - 30
Database
ISI
SICI code
0365-0375(1994)82:1<25:CMOG-O>2.0.ZU;2-A
Abstract
The preparation of an O-carboxymethylated derivative of heparan sulpha te is reported. The product was studied by methanolysis and GLC-MS. An ionic charge was increased in 20% and the resulting product was suscep tible to heparinase degradation.