Sa. Pergantis et al., SIMPLEX OPTIMIZATION OF CONDITIONS FOR THE DETERMINATION OF ARSENIC IN ENVIRONMENTAL-SAMPLES BY USING ELECTROTHERMAL ATOMIC-ABSORPTION SPECTROMETRY, Talanta, 41(2), 1994, pp. 205-209
Simplex optimization was used to efficiently delineate the optimum exp
erimental conditions to be used for the electrothermal atomic absorpti
on spectrometric analysis of arsenic in a standard reference material
of marine origin. Four experimental variables, were considered: ashing
temperature, atomization temperature, modifier concentration, and ato
mization ramping time. This combination of methods and materials provi
des a powerful means of rapidly improving the experimental conditions
used for analysis of arsenic in a wide variety of samples of environme
ntal origin. Excellent recoveries of arsenic were obtained when using
the optimum electrothermal atomic absorption spectrometry conditions t
o analyze standard solutions of arsenobetaine, arsenocholine and tetra
methylarsonium iodide.