Ms. Pena et al., SOLVENT EFFECT ON THE DETERMINATION OF SULFAMETHAZINE BY ROOM-TEMPERATURE PHOTOCHEMICALLY INDUCED FLUORESCENCE, Talanta, 41(2), 1994, pp. 233-236
Room-temperature photochemically-induced fluorescence (RTPF) was appli
ed to the determination of sulfamethazine (SMT) in methanol, ethanol a
nd 2-propanol. Optimal ultraviolet irradiation times ranged between 2
and 6 min. Linear calibration graphs were obtained over a concentratio
n range of more than one order of magnitude. The relative standard dev
iations were within the range 1.4-2.2%. Limits of detection were betwe
en 40 and 80 ng/ml. The method was evaluated for its applicability to
the analysis of SMT in pharmaceutical formulations.