Stuttering is increasingly being recognised as a neurodevelopmental di
sorder. This has stimulated new interest in pharmacological approaches
to the treatment of the condition. Psychosocial factors are also rega
rded as important to the course of the condition. Therefore, psychosoc
ial interventions, such as psychotherapy and speech retraining, are im
portant components of a comprehensive treatment programme. A wide rang
e of pharmacological agents are effective in reducing stuttering in se
lected patients. These include haloperidol, verapamil, bethanechol and
some antidepressants. The agents are presumed to work through differe
nt mechanisms. Unilateral injection of botulinum toxin directly into t
he vocal folds is another promising treatment.