NITRIC-OXIDE - MEDIATOR, MURDERER, AND MEDICINE

Authors
ANGGARD E
Citation
E. Anggard, NITRIC-OXIDE - MEDIATOR, MURDERER, AND MEDICINE, Lancet, 343(8907), 1994, pp. 1199-1206
Citations number
60
Categorie Soggetti
Medicine, General & Internal
Journal title
Lancet → ACNP
ISSN journal
01406736
Volume
343
Issue
8907
Year of publication
1994
Pages
1199 - 1206
Database
ISI
SICI code
0140-6736(1994)343:8907<1199:N-MMAM>2.0.ZU;2-X
Abstract
In the past ten years several research fields have converged to show t hat the tiny molecule nitric oxide (NO), a reactive gas, functions bot h as a signalling molecule in endothelial and nerve cells and as a kil ler molecule by activated immune cells-and it can be used as a new med icine by inhalation. This article reviews the biology of this remarkab le molecule and discusses the implications for clinical medicine.