PASSIVE IMMUNOTHERAPY WITH VENIMMUN(R) FOR THE PREVENTION OF HABITUALABORTIONS - EARLY-PREGNANCY FACTOR, PLACENTAL PROTEIN-12, PLACENTAL PROTEIN-14, TUMOR-NECROSIS-FACTOR-ALPHA - PARAMETERS OF CONTROL OF IMMUNOTHERAPY

In a study it was investigated to what extent the early pregnancy fact or, the placental proteins 12 and 14 and tumor necrosis factor alpha a re suited to control and select patients with habitual abortions for i mmunotherapy. Immunotherapy shows good clinical results. Placental pro tein 12 ist not suited for selecting patients. Placental protein 14 sh ows typical changes after the application of polyvalent immunoglobulin and could be an important prognostic factor. Tumor necrosis factor al pha seems to be useful for selecting patients for immunotherapy, becau se in cases of habitual abortions this factor can be a sign for immuno logical causes. In the late phase of pregnancy, early pregnancy factor is also an indicator for disturbances of pregnancy.