MULTIPLE AND DISTINCT PRIMARY CANCERS - A CASE-REPORT

Multiple primary cancers in a single individual are rare when more tha n three distinct lesions are considered. This article reports a patien t who developed four separate primary cancers: squamous cell carcinoma of the larynx, squamous carcinoma of the lung, adenocarcinoma of the breast, and adenocarcinoma of the colon. No specific hereditary syndro me could be identified from this patient's pedigree. Individuals with a history of multiple cancers should have a complete family history ev aluation and follow-up for development of subsequent primaries.