En. Kaufman et al., SCREENING OF RESINS FOR USE IN A BIPARTICLE FLUIDIZED-BED BIOREACTOR FOR THE CONTINUOUS FERMENTATION AND SEPARATION OF LACTIC-ACID, Applied biochemistry and biotechnology, 45-6, 1994, pp. 545-554
A continuous particle fluidized-bed reactor is being developed for the
simultaneous fermentation and purification of lactic acid. Unlike con
ventional fermentation schemes, the biparticle fluidized bed does not
require the addition of salts for reactor pH control and product separ
ation as the inhibitory product is removed directly from the reactor.
This minimizes process waste and enhances reactor efficiency. This wor
k has screened a series of adsorbents for possible utilization in the
biparticle fluidized-bed fermentation of lactic acid by immobilized La
ctobacillus delbreuckii. Capacity, specificity, regenerability, and ki
netics were investigated. Although a resin exhibiting all of the desir
ed properties has yet to be found, Remex 425 appears satisfactory and
will be utilized in initial process demonstration as resin screening c
ontinues.