There have been many advances in the mapping of disease mortality and
morbidity rates in recent years. An increasingly common approach is to
calculate ''stabilized'' rates for individual geographic areas by inc
orporating information from the entire set of data. One such method, a
dopted by the National Cancer Institute for its mortality maps, is des
cribed and applied to national end-stage renal disease data. Some poss
ible difficulties in interpretation are noted, resulting from: (1) ins
ufficient shrinkage, (2) highly skewed rate distributions, (3) differe
nt denominator distributions, and (4) variations in population density
.