ASSESSMENT OF THE EFFECT OF OVARIAN SUPPRESSANTS ON WOMEN WITH THE PREMENSTRUAL-SYNDROME - ITERATIVE SPECTRAL-ANALYSIS

The daily mood symptoms of four women with the premenstrual syndrome ( PMS) were recorded before, and after spontaneous or induced ovarian fa ilure. Response was assessed by iterative spectral analysis and the re sults compared with techniques based on changes in the mean or median mood score, or the measurement of premenstrual tension in arbitrary 'm enstrual' cycles. Only iterative spectral analysis had the capacity to establish the significance of a change in symptom cyclicity, an impor tant attribute for a condition such as the PMS.