The entire prostate of a 10 year old boy was cut with a microtome into
4300 serial slices. The nerves were stained using a monoclonal antibo
dy called anti PS 100. All information was recorded using a computer r
econstruction programme. The prostatic nerve supply is very abundant.
The nerve fibers of the cranial prostate (central zone) follow a pathw
ay parallel to the anterior surface of the seminal vesicles going towa
rds the caudal prostate. The periurethral zone is widely innervated by
nerves arising from the periphery. The caudal prostate also contains
many nerve fibers of variable size. We identified many nerve fibers al
ong the anterior surface of the seminal vesicles and surrounding the l
ateral aspect of the prostatic capsule. They penetrate the capsule and
the whole circumference of the caudal prostate. The prostatic capsule
is covered by numerous nerve fibers and ganglia, which form a true pe
riprostatic nerve network. The urethra is supplied by numerous thick f
ibers of more than 30 mum in diameter.