This study assessed the frequency and type of sexual disorders associa
ted with Huntington's disease (HD) in an unbiased sample. Of 39 HD pat
ients and 32 of their partners, 82% and 66%, respectively, had one or
more sexual disorders by DSM-III-R criteria. The most frequent for bot
h groups was hypoactive sexual disorder. Significantly more patients w
ho had both inhibited orgasm and increased sexual interest also had pa
raphilic disorders. Findings support the hypotheses that sexual disord
ers are frequent among HD patients and their partners and that sexual
disorders among HD patients may take the form of increased sexual inte
rest or paraphilias. The association between inhibited orgasm, increas
ed sexual interest, and paraphilic disorders will require further inve
stigation but suggests a possible etiology for some paraphilias.