ANTIGENIC PROPERTIES OF HERPES-SIMPLEX VI RUS TYPE-1 AND TYPE-2 RECOMBINANT PROTEINS AND THE USE THEREOF FOR ENZYME-IMMUNOASSAY DETECTION OF HERPES ANTIBODIES

Authors
ZVONAREV AY KLICHKO VI SHATALIN KY KARASEVA EV KULYAKINA MN
Citation
Ay. Zvonarev et al., ANTIGENIC PROPERTIES OF HERPES-SIMPLEX VI RUS TYPE-1 AND TYPE-2 RECOMBINANT PROTEINS AND THE USE THEREOF FOR ENZYME-IMMUNOASSAY DETECTION OF HERPES ANTIBODIES, Voprosy virusologii, 39(2), 1994, pp. 59-62
Citations number
8
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
39
Issue
2
Year of publication
1994
Pages
59 - 62
Database
ISI
SICI code
0507-4088(1994)39:2<59:APOHVR>2.0.ZU;2-A
Abstract
The structural and nonstructural recombinant proteins oi HSV type 1 an d type 2 were expressed in E. coli by fusion with cro-beta-galactosida se proteins. These proteins containing amino acid sequences of ICP4, I CP27, ICP47, ICP22, major capsid protein and major DNA binding protein s oi HSV types 1 and 2 reacted in immunoblotting with the correspondin g anti-HSV sera from hyperimmune rabbits. The nonstructural recombinan t proteins can be used for enzyme immunoassay detection oi HSV1 or HSV 2 type-specific antibodies in sera from patients with acute HSV infect ion.