MAPPING OF HEMAGGLUTININ SITES OF INFLUEN ZA H3N2 VIRUSES ISOLATED IN1990-1993

Authors
ISAEVA EI IVANOVA VT ROVNOVA ZI OSKERKO TA ALIPOVA TA
Citation
Ei. Isaeva et al., MAPPING OF HEMAGGLUTININ SITES OF INFLUEN ZA H3N2 VIRUSES ISOLATED IN1990-1993, Voprosy virusologii, 39(2), 1994, pp. 62-65
Citations number
9
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
39
Issue
2
Year of publication
1994
Pages
62 - 65
Database
ISI
SICI code
0507-4088(1994)39:2<62:MOHSOI>2.0.ZU;2-D
Abstract
The antigenic structure of hemagglutinin (HA) of influenza A (H3N2) vi ruses was found to have undergone significant changes which markedly d istinguished the new isolates of previously occurring strains. Investi gations of the epidemic variants using monospecific and monoclonal ant ibodies revealed strains with original HA sites previously unfound in H3N2 viruses. The emergence of the sites with the new properties deter mined the epidemic activity of the viruses isolated in this period.