ROCKET IMMUNOELECTROPHORESIS FOR EVALUATI ON OF GLYCOPROTEIN CONTENT IN CONCENTRATED RABIES VACCINES

Rocket immunoelectrophoresis (RIE) was shown to be useful for the eval uation of glycoprotein (GP) content in concentrated rabies vaccines, a nd disintegron B., a zwitterionic detergent made in this country, for treatment of the vaccines for these evaluations. The values of GP cont ent obtained by RIE and single radial immunodiffusion test were simila r. The highest values were obtained for all the vaccines tested with a nti-PM GP serum compared with anti-ERA and Vnukovo-32 GP serum. When a nti-PM and anti-Vnukovo-32 GP sera were used for RIE two components we re revealed in the vaccines. All the preparations under study containe d soluble GP.