ROCKET IMMUNOELECTROPHORESIS FOR EVALUATI ON OF GLYCOPROTEIN CONTENT IN CONCENTRATED RABIES VACCINES

Citation
Ra. Volkova et al., ROCKET IMMUNOELECTROPHORESIS FOR EVALUATI ON OF GLYCOPROTEIN CONTENT IN CONCENTRATED RABIES VACCINES, Voprosy virusologii, 39(2), 1994, pp. 68-71
Citations number
8
Categorie Soggetti
Virology
Journal title
ISSN journal
05074088
Volume
39
Issue
2
Year of publication
1994
Pages
68 - 71
Database
ISI
SICI code
0507-4088(1994)39:2<68:RIFEOO>2.0.ZU;2-9
Abstract
Rocket immunoelectrophoresis (RIE) was shown to be useful for the eval uation of glycoprotein (GP) content in concentrated rabies vaccines, a nd disintegron B., a zwitterionic detergent made in this country, for treatment of the vaccines for these evaluations. The values of GP cont ent obtained by RIE and single radial immunodiffusion test were simila r. The highest values were obtained for all the vaccines tested with a nti-PM GP serum compared with anti-ERA and Vnukovo-32 GP serum. When a nti-PM and anti-Vnukovo-32 GP sera were used for RIE two components we re revealed in the vaccines. All the preparations under study containe d soluble GP.