THE IMPORTANCE OF MIXED CONGENITAL VIRUS- INFECTION IN THE ANTENATAL AND PERINATAL HUMAN PATHOLOGY

Examinations of 202 newborn babies for a representative group of viral infections by detection of viral antigens in cells of urine sediment and in the autopsy materials by indirect immunofluorescence permitted diagnosis of a congenital viral infection in 92 % of patients with int rauterine and perinatal pathology; in 72.5 % it was a mixed infection. In the patients the virus-virus associations were, as a rule, represe nted by enteroviruses of Coxsackie group and/or influenza A, B, and C viruses. Most frequently (83.3-100 %) mixed virus infection was detect ed in newborn babies with the severest pathology (meningoencephalitis, encephalitis, sepsis, intrauterine pneumonia), as well as in fatal ca ses.