Tv. Amvrosieva et al., VIRUS-INDUCED DYSLIPIDEMIAS AS POSSIBLE R ISK-FACTORS IN THE DEVELOPMENT OF SOMATIC DISEASES, Voprosy virusologii, 39(2), 1994, pp. 87-91
Experimental and clinical studies showed a number of virus infections
to be accompanied by lipidemic disorders. Experimentally, dyslipidemia
s were found in tick-borne encephalitis (TBE) in mice, rotavirus infec
tion in rabbits, and amyotrophic leukospongiosis in guinea pigs. The p
ossibility of correcting the virus-induced lipidemic disorders with an
antiviral drug, lyncomycine, was demonstrated in TBE in mice. Dynamic
study of the lipidemic status of patients with Virus hepatitis A reve
aled marked dyslipidemia of the atherogenic type which was stable and
persisted up to the time of clinical recovery. The data obtained suppl
ement the current concepts concerning the pathogenesis of virus infect
ions.