Peripheral vascular complications after cardiac catheterization consti
tute an increasing portion of traumatic vascular injuries. To determin
e the incidence of these complications and the sequelae of their treat
ment, we reviewed 7,690 catheterizations performed over a 40-month per
iod. One hundred eleven vascular complications were detected (1%), 41
of which required surgical repair (0.5%). Pseudoaneurysm (10), arterio
venous fistula (4), thromboembolism (9), infection (5), and other blee
ding complications (83) were all found. Significantly more complicatio
ns occurred in patients who were older than 60 years of age or female
(P <0.0009). In addition, the likelihood of a vascular injury after co
ronary angioplasty was significantly higher than after angiography alo
ne (3% versus 1%, P <0.00001). Secondary local and systemic complicati
ons after surgical repair were more frequent compared with those injur
ies that were managed nonoperatively (32% versus 11%; P = 0.015). Vasc
ular complications continue to be a significant problem after cardiac
catheterization, especially when coronary angioplasty is performed. Th
e sequelae of surgical repair are significant, adding to their morbidi
ty. Periodic review of these complications may identify factors that m
ight be modified to reduce complications.