Cj. Shishoo et al., SYNTHESIS OF SOME TITUTED-6-PHENYL-THIENO(3,2-D)PYRIMIDIN-4(3H)-ONES AND 7-PHENYL-THIENO[3,2-D]PYRIMIDIN-4(3H)-ONES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(5), 1994, pp. 436-440
The title compounds, 7a-j and 8a-c, have been prepared through cycloco
ndensation of the corresponding thiophene o-aminoesters (5a and 5b) wi
th a variety of nitriles in the presence of dry hydrogen chloride gas.