H. Alp et al., ULTRASTRUCTURAL-CHANGES OF EPIDERMAL LANGERHANS CELLS IN PREGNANT GUINEA-PIGS - A PRELIMINARY-REPORT, Acta anatomica, 149(2), 1994, pp. 100-103
An association between pregnancy and a depression in cellular immunity
has long been, known, but the reason for this is far from clear. To i
nvestigate the possible role of Langerhans cells (LC) in immunosuppres
sion during pregnancy, we examined the epidermal LC morphology of preg
nant guinea pigs ultrastructurally. An altered morphology of epidermal
LCs was observed in all specimens obtained from pregnant guinea pigs.
LCs were found to be activated in pregnancy.