BACKGROUND: Smoking is the main cause of preventable morbidity and mor
tality in Europe. The effect of smoking is not constant with the disea
ses related to it The goal of this study is to estimate poblational et
iologic fractions (PEF), as the proportion of disease attributable to
smoking in the reference population, for those disease clearly related
to smoking in Granada. METHODS: The PEF depend upon relative risk (RR
) and the proportion of exposed subjects in the target population. Met
a-analytic procedures, following the Woolf's method, were applied to e
stimate weighted RR between smoking and each one of the diseases studi
ed. A survey on a random sample of all Granadian population to assess
the prevalence of smoking was performed. RESULTS: The PEF were always
higher for males than for females. In males, the highest figures were
for lung cancer (85%) and chronic obstructive lung disease (84%); whil
st in females lung cancer and peripheral artery disease reached the gr
eatest figures, 55% and 51%, respectively. CONCLUSIONS: The figures ob
tained outlight the need of improving antismoking campaigns and allow
to quantify the maximum potential benefit to be got if smoking was qui
t by the Granadian population.