SYNTHESIS AND ODOR OF CHIRAL PARTIAL STRUCTURES OF KHUSIMONE .1.

Authors
SPREITZER H PICHLER A HOLZER W TOTH I ZUCHART B
Citation
H. Spreitzer et al., SYNTHESIS AND ODOR OF CHIRAL PARTIAL STRUCTURES OF KHUSIMONE .1., Helvetica Chimica Acta, 80(1), 1997, pp. 139-145
Citations number
26
Categorie Soggetti
Chemistry
Journal title
Helvetica Chimica Acta → ACNP
ISSN journal
0018019X
Volume
80
Issue
1
Year of publication
1997
Pages
139 - 145
Database
ISI
SICI code
0018-019X(1997)80:1<139:SAOOCP>2.0.ZU;2-6
Abstract
Khusimone (1), one of the main odor-donating compounds of vetiver oil is subject of the following study on structure/odor relationship. The omittance of the ethano bridge of the tricyclic khusimone leads to a b icyclic system. The stereoselective approach to this degraded structur e is described, and the olfactory properties are studied. The key step of the synthesis of the hydrindane nucleus is based on a highly diast ereoselective conjugate addition to a chiral oxo-cyclopentene-2-carbox ylate.