INTERFERENCE BY SPIRONOLACTONE ON ADRENOCORTICAL SCINTIGRAPHY AND OTHER PITFALLS IN THE LOCATION OF ADRENAL ABNORMALITIES IN PRIMARY ALDOSTERONISM

Citation
B. Shapiro et al., INTERFERENCE BY SPIRONOLACTONE ON ADRENOCORTICAL SCINTIGRAPHY AND OTHER PITFALLS IN THE LOCATION OF ADRENAL ABNORMALITIES IN PRIMARY ALDOSTERONISM, Clinical nuclear medicine, 19(5), 1994, pp. 441-445
Citations number
29
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
ISSN journal
03639762
Volume
19
Issue
5
Year of publication
1994
Pages
441 - 445
Database
ISI
SICI code
0363-9762(1994)19:5<441:IBSOAS>2.0.ZU;2-T
Abstract
A case of primary aldosteronism is presented in which the CT scan was initially misleading, adrenocortical scintigraphy was rendered inaccur ate by pharmacological interference of spironolactone, and selective a drenal venous sampling of aldosterone was technically difficult. When dexamethasone suppression adrenocortical scintigraphy was performed wi th attention to technical detail and exclusion of interference by spir onolactone, the causative lesion was scintigraphically demonstrated. T his finding was confirmed by the results of venous sampling and the co rrectly located tumor removed.