Purpose: The authors studied the orbital hemodynamics of patients with
nonvascular and nonglaucomatous optic neuropathy. Methods: The author
s performed orbital color Doppler imaging on 19 eyes of 10 patients wi
th compressive, inflammatory, toxic, or hereditary optic neuropathy, T
he peak systolic velocity (PSV), end diastolic velocity (EDV), and Pou
rcelot's resistivity (PR) index of the central retinal, temporal short
posterior ciliary, nasal short posterior ciliary, and ophthalmic arte
ries were assessed. Statistical comparison of these values was perform
ed against ten normal controls of similar age and gender using the two
-sample Student's t test. Results: No statistical significance was fou
nd in the PSV, EDV, and PR of the central retinal, temporal short post
erior ciliary, nasal short posterior ciliary, and ophthalmic arteries
between the optic atrophy and control groups and analysis of 95% confi
dence intervals for these variables suggested that the true difference
s between these groups were small. Conclusions: This study suggests th
at optic atrophy in and of itself does not appear to alter orbital hem
odynamics to the extent previously demonstrated for glaucoma patients.