SYRINGOCYSTADENOMA PAPILLIFERUM OF THE EYELID

Syringocystadenoma papilliferum is a benign adnexal tumor of the scalp and face. We treated syringocystadenoma papilliferum in a 31-year-old man who had a circumscribed cup-shaped lesion of the left upper eyeli d with a central crater. On histologic examination, the epidermal edge showed hyperkeratosis and invasive acanthosis with papillary projecti ons that filled the central crater. The deeper portions of the project ions resembled ductal structures lined by an inner columnar epithelium , which demonstrated luminal apical decapitation secretions, and an ou ter layer of smaller cuboidal cells. The fibrovascular dermal tissue e xhibited prominent plasmacytic infiltration underlying the papillary e pithelium. Although rare, syringocystadenoma papilliferum should be co nsidered in the differential diagnosis of umbilicated squamous or basa l cell tumors, especially if noted in a young individual.