CHROMOSOMAL LOCALIZATION AND SEQUENCES OF THE MURINE BRN-3 FAMILY OF DEVELOPMENTAL CONTROL GENES

Authors
THEIL T ZECHNER U KLETT C ADOLPH S MOROY T
Citation
T. Theil et al., CHROMOSOMAL LOCALIZATION AND SEQUENCES OF THE MURINE BRN-3 FAMILY OF DEVELOPMENTAL CONTROL GENES, Cytogenetics and cell genetics, 66(4), 1994, pp. 267-271
Citations number
11
Categorie Soggetti
Cytology & Histology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
66
Issue
4
Year of publication
1994
Pages
267 - 271
Database
ISI
SICI code
0301-0171(1994)66:4<267:CLASOT>2.0.ZU;2-G
Abstract
The POU proteins BRN-3a, -3b and -3c are transcription factors encoded by separate genes that are differentially expressed during neural dev elopment. Comparison of genomic and cDNA sequences revealed similar ex on/intron structures for Brn-3a and -3c genes, whereas the Brn-3b gene appeared to contain an intronless coding region. Fluorescence in situ hybridization experiments with mouse chromosomes showed that Brn-3a m aps to mouse chromosome 14E1-3, Brn-3b to XF1-5 and Brn-3c to 18B3-E1.