To determine the influence of the underlining disease on the duration
of total parenteral nutrition (TPN) and on the long-term prognosis, da
ta from 30 admitted patients with permanent (n = 23) and temporary (n
= 7 short bowel syndrome were retrospectively analyzed and the present
status of all living patients evaluated. Patients with <<permanent sh
ort bowel>> after thrombosis of the superior mesenteric artery (group
I, n = 13) or malignant tumours (group II, n = 3) had a decreased surv
ival compared to patients with other causes such as ileus, intestinal
volvulus-thrombosis of mesenteric veins or benign tumors (group III, n
= 7). Whithin the first six postoperative months, all patients in gro
up I and all patients in group II died of the underlying disease where
as none died in group III. One patient in group I and one patient in g
roup III died as a result of complications related to TPN. The differe
nt underlying diseases had no influence on the adaptation of the small
intestine or on the duration of TPN in the surviving patients. Return
to enteral autonomy seems to mainly depend on the length of the remai
ning small and large bowel and early enteral feeding. Complications of
parenteral nutrition and possible options for the surgical treatment
of the shorthowell syndrome are discussed.