Widespread use of echography and laparoscopic surgery has caused a rev
olution in the treatment of gall stones. The question now is which pat
ients should be treated, and when and how? One clear answer concerns a
symptomatic cases: no one. The only patients which might benefit from
''prophylactic cholecystectomy'' are potential graft recipients, altho
ugh no evaluation has been performed. For cholesterol stones, drugs ca
n be effective if the bladder functions correctly. Their effect can so
metimes be accelerated with extracorporal lithotripsy. The indications
of intracorporal lithotripsy are limited by the risks involved. But t
he big breakthough came with laparoscopic procedures, now performed by
nearly all surgeons because of the major improvements in patient comf
ort. This new technique reduces abdominal pain and scar tissue formati
on with the subsequent gain in hospitalization time. In the very near
future, laparoscopic cholecystectomy will undoubtedly be considered th
e reference surgical technique, although until the question of systema
tic peroperative opacification of the main bile duct has been totally
solved, traditional laparotomy will continue to have first intention i
ndications.