EFFECTS OF TRIALKYLSILYL PROTECTING GROUPS ON THE PHOTOLYSIS OF 1-ALPHA-HYDROXY-PROVITAMIN D-3

Authors
OKABE M SUN RC WOLFF S
Citation
M. Okabe et al., EFFECTS OF TRIALKYLSILYL PROTECTING GROUPS ON THE PHOTOLYSIS OF 1-ALPHA-HYDROXY-PROVITAMIN D-3, Tetrahedron letters, 35(18), 1994, pp. 2865-2868
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
18
Year of publication
1994
Pages
2865 - 2868
Database
ISI
SICI code
0040-4039(1994)35:18<2865:EOTPGO>2.0.ZU;2-X
Abstract
The quantum yield of the photolytic opening of the diene ring of a 1 a lpha-hydroxrprovitamin D-3 analog decreased with an increase in the si ze of the trialkylsilyl group on the 1 alpha-hydroxy group. When the 1 alpha-hydroxy group was protected as a triisopropylsilyl ether (4c), the quantum yield of the photochemical ring-opening reaction was found to be about one-third of that of the parent compound (5).