A STEREOSELECTIVE ROUTE TO ENANTIOMERICALLY PURE MYOINOSITOL DERIVATIVES STARTING FROM D-MANNITOL

Authors
CHIARA JL MARTINLOMAS M
Citation
Jl. Chiara et M. Martinlomas, A STEREOSELECTIVE ROUTE TO ENANTIOMERICALLY PURE MYOINOSITOL DERIVATIVES STARTING FROM D-MANNITOL, Tetrahedron letters, 35(18), 1994, pp. 2969-2972
Citations number
37
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
18
Year of publication
1994
Pages
2969 - 2972
Database
ISI
SICI code
0040-4039(1994)35:18<2969:ASRTEP>2.0.ZU;2-9
Abstract
A carbocyclization route to inositols starling from alditols has been developed involving as a key step a stereoselective intramolecular pin acol coupling of a 1,6-dialdehyde promoted by samarium diiodide. This route has been applied to the synthesis of enantiomerically pure myo-i nositol derivatives using readily available D-mannitol as starting mat erial