We report the MR imaging findings in two patients with solitary cranio
cerebral plasmacytoma, a benign plasma cell tumor that can arise from
the skull, the dura, or, rarely, the brain. In both patients, the lesi
on was extraaxial and nearly isointense with gray matter on T2-weighte
d MR images, and diffusely enhanced after administration of contrast m
aterial, bearing some similarities to meningioma, A diagnosis of solit
ary craniocerebral plasmacytoma should be considered when a mass with
these imaging features is seen, because total excision may not be nece
ssary for this radiosensitive tumor.