NOVEL SEQUENCE-TAGGED SITES FROM THE HUMAN 8P12-P21 CHROMOSOMAL REGION INVOLVED IN BREAST-CANCER

Authors
CHAFFANET M POPOVICI C IMBERT A SAMSON D BIRNBAUM D PEBUSQUE MJ
Citation
M. Chaffanet et al., NOVEL SEQUENCE-TAGGED SITES FROM THE HUMAN 8P12-P21 CHROMOSOMAL REGION INVOLVED IN BREAST-CANCER, Oncology Reports, 4(2), 1997, pp. 367-369
Citations number
11
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
4
Issue
2
Year of publication
1997
Pages
367 - 369
Database
ISI
SICI code
1021-335X(1997)4:2<367:NSSFTH>2.0.ZU;2-8
Abstract
Seventeen sequence-tagged sites (STSs) from the human 8p12-p21 chromos omal region were identified in a subset of nonchimeric yeast artificia l chromosomes (YACs). YAC ends were cloned, sequenced and a PCR primer pair was designed for each of the STSs thus generated. STSs were mapp ed by means of PCR on somatic cell hybrids specific for chromosome 8. These STSs will contribute to the construction of physical, high-resol ution genetic and transcriptional maps necessary to clone potential tu mor suppressor genes of the 8p12-p21 region involved in breast cancer.