FURTHER-STUDIES ON THE ADJUVANTICITY OF STEARYL TYROSINE AND AMIDE ANALOGS

Authors
PENNEY CL DIONNE G NIXONGEORGE A BONA CA
Citation
Cl. Penney et al., FURTHER-STUDIES ON THE ADJUVANTICITY OF STEARYL TYROSINE AND AMIDE ANALOGS, Vaccine, 12(7), 1994, pp. 629-632
Citations number
9
Categorie Soggetti
Immunology
Journal title
Vaccine → ACNP
ISSN journal
0264410X
Volume
12
Issue
7
Year of publication
1994
Pages
629 - 632
Database
ISI
SICI code
0264-410X(1994)12:7<629:FOTAOS>2.0.ZU;2-T
Abstract
Stearyl tyrosine has been described in the literature as a candidate a juvant for human vaccines. More recently, other stearyl esters have be en reported to be adjuvant-active. This preliminary study assesses the adjuvanticity of stearyl amides, including the amide analogue of stea ryl tyrosine: tyrosyl stearylamine. This study indicates that phenylal anylethanolamine O-stearate induces a significant antibody response an d a favourable isotype distribution.