BIOENERGETIC CONSEQUENCES IN THE INTERACTION OF MAMMALIAN-CELL AND VIRUS FOR THE MULTIPLICATION OF RECOMBINANT VACCINIA AND EXPRESSION OF HETEROLOGOUS PROTEIN (BETA-HCG)

Authors
MUKHOPADHYAY A MUKHOPADHYAY SN TALWAR GP
Citation
A. Mukhopadhyay et al., BIOENERGETIC CONSEQUENCES IN THE INTERACTION OF MAMMALIAN-CELL AND VIRUS FOR THE MULTIPLICATION OF RECOMBINANT VACCINIA AND EXPRESSION OF HETEROLOGOUS PROTEIN (BETA-HCG), Biotechnology letters, 16(4), 1994, pp. 339-344
Citations number
17
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
4
Year of publication
1994
Pages
339 - 344
Database
ISI
SICI code
0141-5492(1994)16:4<339:BCITIO>2.0.ZU;2-F
Abstract
Energy generation in vaccinia virus infected Vero cell is investigated . The specific ATP pool in infected cells increases in the range of 40 -80%, in contrast to uninfected cells. Virus replication and beta-hCG expression are associated with the drop in ATP/ADP ratio from 7.0 to 2 .5. High initial infection level leads to more energy generation and a lso more product formation.