SEQUENCE OF THE RAD55 GENE OF SACCHAROMYCES-CEREVISIAE - SIMILARITY OF RAD55 TO PROKARYOTIC RECA AND OTHER RECA-LIKE PROTEINS

Authors
LOVETT ST
Citation
St. Lovett, SEQUENCE OF THE RAD55 GENE OF SACCHAROMYCES-CEREVISIAE - SIMILARITY OF RAD55 TO PROKARYOTIC RECA AND OTHER RECA-LIKE PROTEINS, Gene, 142(1), 1994, pp. 103-106
Citations number
20
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
142
Issue
1
Year of publication
1994
Pages
103 - 106
Database
ISI
SICI code
0378-1119(1994)142:1<103:SOTRGO>2.0.ZU;2-C
Abstract
The RAD55 gene is required for radiation resistance and meiotic viabil ity and presumably acts in recombination and recombinational DNA repai r pathways. The nucleotide (nt) sequence of RAD55 from Saccharomyces c erevisiae was determined. The amino-acid sequence predicted from the n t sequence showed similarity to the RecA protein of bacteria and the R ecA-like proteins from yeast: RAD51, RAD57 and DMC1. Similarity was st rongest in the region of RecA that interacts with ATP cofactor.