NMR-STUDIES OF THE KINETICS OF HOMOGENEOUSLY CATALYZED HYDROGENATIONSUSING PARAHYDROGEN INDUCED POLARIZATION AT VARIABLE-PRESSURE

Quantitative evaluation of Parahydrogen Induced Polarization (PHIP) ex periments provides for the determination of kinetic data of homogeneou sly catalyzed hydrogenations. Especially developed NMR probes facilita te investigations at reproducible reaction conditions and constant hyd rogenation rates. Rate equations, describing the experimentally achiev ed steady state kinetics, are used to determine the pressure dependent ratio between free and complexed catalyst in the reactive solution du ring the hydrogenation. A method is presented to determine the rate co nstants of the catalytic cycle of such hydrogenations, which follow th e hydride route.