L. Szente et al., FATTY-ACID CYCLODEXTRIN COMPLEXES - PROPERTIES AND APPLICATIONS, Journal of inclusion phenomena and molecular recognition in chemistry, 16(4), 1993, pp. 339-354
The complexation of fatty acids (both saturated and unsaturated) with
various cyclodextrins and cyclodextrin derivatives greatly modifies th
eir properties. Inclusion complex formation - depending upon the type
of host cyclodextrin - may result in protection against the environmen
t, in improved water solubility and bioavailability. Thus lipid comple
xation enables the preparation of more reliable diagnostic reagents, b
etter chromatographic separations and higher yields in biotechnologica
l processes. The relevant literature is reviewed with particular empha
sis on the practical utility of the molecular encapsulation of fatty a
cids with cyclodextrins.