The size of the normal spleen was estimated by CT in 153 children, exa
mined with indication unrelated to splenic disease. In each patient th
e width, thickness, length and volume of the spleen were calculated. M
easurements were also normalized to the transverse diameter of the bod
y of the first lumbar vertebra. The spleen underwent significant growt
h during the first 4 years of life and reached maximum size at the age
of 13. There were no differences in splenic volume between boys and g
irls. Splenic thickness correlated best with normal splenic volume. Th
e strongest correlation was also found between splenic thickness and v
olume in a group of 45 children with clinically evident splenomegaly.
Splenic thickness, an easy-to-use measurement, may be employed in ever
yday practice to represent splenic volume on CT.