The aim of the study was to establish neonatal prognosis in cases of P
ROM onset in early pregnancy. Pregnancies included in a multicenter st
udy. Group (E) are 16 pregnant women with PROM between 23 and 27 weeks
of gestation. Group (D) are 22 pregnant women with PROM between 28 an
d 30 weeks of gestation. Group (E) women delivered between 24-36 weeks
(x = 29.25 w; SE 0.92; confidence 95%: 27.2 - 31.2 w). 5/16 newborns
died, two in the delivery room and three in the first days of life. Su
rvival in this group was 11/16 (68.75%). 8/14 suffered from respirator
y distress syndrome (RDS), severe in six. 2/14 newborns suffered from
early onset sepsis and 6/14 intraventricular hemorrhage (IVH). Group (
D) women delivered between 2836 weeks (x 30.48 w; SE 0.38; confidence
95%: 29.6 - 31.2 w. Only one newborn died from sepsis (Streptococcus a
galactiae). Survival in this group was 21/22 (95.45%). 5/21 newborns s
uffered from RDS, severe only in one. Early onset sepsis in 2/22 and I
VH 6/21. Infection has a high incidence in newborn infants with PROM.
Mortality is related to respiratory distress syndrome. The most common
problems are respiratory distress syndrome and intraventricular hemor
rhage.